Endocrine Abstracts

Introduction: The prevalence of autoimmune thyroid diseases in patients with type 1 diabetes mellitus (T1DM) is high. Thyroid hormones have a pronounced effect on the regulation of glucose homeostasis. We report patient with well controlled T1DM and good compliance, presented with severe diabetic ketoacidosis (DKA) due to thyrotoxicosis.Case report: A 15-year-old girl with well-controlled T1DM for 5 years (HbA1c<8%) had no tissue complications of dia...

Introduction: Autoimmune polyglandular syndrome type 1 (APS1) – severe disease that is rare in pediatric practice. Clinical sings of APS1 are quite diverse, new components may manifest at any age. Their timely diagnosis is critically important, some symptoms can threaten patient’s life. We present our own clinical observation of the APS1 course in siblings.Case report: A 10-year-old previously healthy boy presented with severe weakness, drowsin...